PT-141 10mg 3ml Research Peptide

PT-141 10mg: Research Grade Bremelanotide Peptide

Biomolecular Action & Research Scope

PT-141, also known as Bremelanotide, is a peptide and a log of the endogenous alpha-melanocyte-stimulating hormone. If we talk about the structure, it is known to be an active metabolite of Melanotan-2, but it completely lacks the C-terminal function. It significantly changes the receptor binding characteristics.

Unlike all the other Melanocortin variants, it targets the peripheral skin pathways. PT 141 is studied extensively because of its ability to cross the blood-brain barrier and also work directly in the central nervous system.

Primary Areas of In-Vitro Evaluation

In biomolecular models, researchers use this peptide to find nonselective agonist activities through the multiple Melanocortin receptor families. The research focuses on

• Central MC4R & MC3R Activation: finding how the peptides actually interact with the central nervous system pathways to start the neurochemical and appetitive behavioral responses.
• Dopaminergic Signaling Pathways: assessing the downstream signaling links between the dopamine release and melanocortin receptor binding in all the targeted brain regions.
• Cyclic Ring Stability: structural studies finding how the cyclic lactam bridge resists degradation when subjected to systemic proteins in all the laboratory assessments.

Reconstitution & Cold-Chain Stability

To avoid the premature denaturation of the peptides and preserve their integrity for the analytical data, you have to adhere to particular environmental parameters that are as follows

• Lyophilized Storage (Unopened Powder): If the powder is unopened, you can keep it for up to two years by storing it in a stable freezer at -20°C.
• Ambient Buffering (Short-Term): If you have to use it immediately for testing and are going to utilize it in 14 to 21 days, then you can store it at 4°C, but completely away from direct light.
• Liquid Stability Window: Once you have mixed the proper liquid laboratory solvent into it, you have to strictly store it at about 4°C. You must also ensure you use it within 20 days, the structural integrity of the peptide can be affected severely.

Key Features

• Cyclic heptapeptide — Melanotan II derivative
• Melanocortin receptor agonist (MC1R, MC3R, MC4R, MC5R)
• ≥99% purity — HPLC tested, COA provided
• 10mg research vial — lyophilised powder
• Fast UK dispatch

Specifications

• Molecular Formula: C₅₀H₆₈N₁₄O₁₀
• Molecular Weight: 1025.17 g/mol
• Purity: ≥99% (HPLC)
• Form: Lyophilised powder
• Storage: −20°C long-term; 4°C post-reconstitution

For research use only. Not intended for human consumption.