{"product_id":"hgh-fragment-10mg-3ml-research-peptides-in-uk","title":"HGH Fragment 10mg 3ml Research Peptides in UK - 99% Purity","description":"\u003ch2\u003eHGH Fragment 176-191 10mg | Research Peptide | 3ml Vial\u003c\/h2\u003e\n\n\u003cp\u003eHGH Fragment 176-191 is a synthetic peptide corresponding to the C-terminal region of Human Growth Hormone (HGH), specifically amino acids 176 through 191 of the 191-amino-acid HGH chain. It was developed through research initiated at Monash University, Australia, with the aim of isolating the lipolytic properties of HGH from its other biological activities. The fragment retains the structural elements of the HGH C-terminus responsible for interactions with adipose tissue, while lacking the N-terminal domain required for binding to the Growth Hormone Receptor (GHR).\u003c\/p\u003e\n\n\u003cp\u003eAs HGH Fragment 176-191 does not bind to the GH receptor, it does not trigger the IGF-1-mediated proliferative signalling cascade associated with full-length HGH. It also does not affect fasting insulin levels or glucose tolerance in research models, making it a useful tool for studies that require dissociation of lipolytic activity from the broader GH signalling axis. The fragment has been studied extensively in preclinical models examining fatty acid metabolism, adipogenesis inhibition, and lipolysis stimulation in isolated adipocytes.\u003c\/p\u003e\n\n\u003cp\u003eThis 10mg\/3ml vial is the highest-concentration format in our HGH Fragment 176-191 range, providing double the research quantity of the 5mg vial in the same convenient 3ml format. Supplied as a sterile lyophilised powder for reconstitution with Bacteriostatic Water.\u003c\/p\u003e\n\n\u003ch3\u003eKey Features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eC-terminal HGH fragment — amino acids 176 through 191 of the native 191 AA sequence\u003c\/li\u003e\n\u003cli\u003eDoes not bind Growth Hormone Receptor (GHR) — no IGF-1 axis stimulation\u003c\/li\u003e\n\u003cli\u003eDoes not alter fasting insulin levels or glucose tolerance in research models\u003c\/li\u003e\n\u003cli\u003eStudied for interactions with lipolysis and fatty acid oxidation pathways in adipocytes\u003c\/li\u003e\n\u003cli\u003e≥99% purity — independently HPLC-verified on every production batch\u003c\/li\u003e\n\u003cli\u003eCertificate of Analysis (COA) provided with every order\u003c\/li\u003e\n\u003cli\u003e10mg\/3ml — highest-concentration format; 2× the content of the 5mg vial\u003c\/li\u003e\n\u003cli\u003eLyophilised powder — superior stability and extended shelf life\u003c\/li\u003e\n\u003cli\u003eFast UK dispatch — same-day available on weekday orders placed before 2pm\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eHGH Fragment 176-191 vs AOD-9604 — Key Differences\u003c\/h3\u003e\n\u003ctable\u003e\n\u003ctr\u003e\n\u003cth\u003eProperty\u003c\/th\u003e\n\u003cth\u003eHGH Fragment 176-191 (this product)\u003c\/th\u003e\n\u003cth\u003eAOD-9604\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSequence\u003c\/td\u003e\n\u003ctd\u003eAA 176–191, no modification\u003c\/td\u003e\n\u003ctd\u003eAA 176–191 + N-terminal Tyr addition\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eN-terminal\u003c\/td\u003e\n\u003ctd\u003eUnmodified (Leu¹⁷⁶)\u003c\/td\u003e\n\u003ctd\u003eTyr-modified for stability\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGHR binding\u003c\/td\u003e\n\u003ctd\u003eNone\u003c\/td\u003e\n\u003ctd\u003eNone\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eIGF-1 effect\u003c\/td\u003e\n\u003ctd\u003eNo change\u003c\/td\u003e\n\u003ctd\u003eNo change\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eResearch origin\u003c\/td\u003e\n\u003ctd\u003eOriginal fragment\u003c\/td\u003e\n\u003ctd\u003eMonash University derivative\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePeptide name\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eHGH Fragment 176-191\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAlso known as\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eHGH Frag 176-191, GH Fragment, HGH 176-191\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSequence\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eLeu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe-NH₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular formula\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eC₇₈H₁₂₃N₂₃O₂₃S₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e~1,817 Da\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eVial content\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e10mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eVial volume\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e3ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePurity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e≥99% (HPLC verified)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eForm\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eLyophilised powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eReconstitution\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eBacteriostatic Water for Injection\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStorage (lyophilised)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e−20°C; protect from light and moisture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStorage (reconstituted)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e2–8°C; use within 14–21 days\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eGHR binding\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eNone\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eIGF-1 effect\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eNo alteration observed in research models\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eGrade\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eResearch Use Only\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eOrigin\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eUK-based supply and dispatch\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\n\u003ch3\u003eReconstitution Guidance\u003c\/h3\u003e\n\u003cp\u003eReconstitute with Bacteriostatic Water for Injection. Add the diluent slowly down the inner wall of the vial — do not inject directly onto the lyophilised cake. Swirl gently to mix; do not vortex or shake vigorously. Allow to stand 2–3 minutes until fully clear and colourless. Store refrigerated at 2–8°C and use within 14–21 days of reconstitution.\u003c\/p\u003e\n\n\u003ch3\u003eRelated Products\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHGH Fragment 176-191 5mg \/ 3ml\u003c\/strong\u003e — entry-level format in this range\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAOD-9604 10mg \/ 3ml\u003c\/strong\u003e — N-terminal Tyr-modified derivative of the same fragment\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBacteriostatic Water 10ml\u003c\/strong\u003e — recommended reconstitution diluent\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e\u003cem\u003eFor research use only. Not intended for human consumption, self-administration, or veterinary use. This product is sold strictly for in vitro and laboratory research purposes. Ultra Peptides accepts no liability for misuse.\u003c\/em\u003e\u003c\/p\u003e","brand":"Ultra Peptides","offers":[{"title":"Default Title","offer_id":47496890253506,"sku":null,"price":99.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0742\/4481\/7090\/files\/HGH-Fragment---10mg---3ml.png?v=1776896122","url":"https:\/\/ultrapeptides.co.uk\/products\/hgh-fragment-10mg-3ml-research-peptides-in-uk","provider":"Ultra Peptides","version":"1.0","type":"link"}