{"product_id":"cjc-1295-10mg-3ml-research-peptide-without-dac","title":"CJC-1295 10mg 3ml Research Peptide (Without DAC)","description":"\u003ch2\u003eCJC-1295 Without DAC 10mg | Research Peptide | 3ml Vial\u003c\/h2\u003e\n\n\u003cp\u003eCJC-1295 Without DAC — also known as Modified GRF 1-29 (Mod GRF 1-29) — is a synthetic analogue of the first 29 amino acids of endogenous Growth Hormone Releasing Hormone (GHRH 1-29). It incorporates four strategic amino acid substitutions relative to the native sequence: Ala²→Aib (α-aminoisobutyric acid), Gln⁸→Ala, Ala¹⁵→Gln, and Leu²⁷→Met. Together these modifications confer resistance to enzymatic degradation — particularly by DPP-IV and endopeptidases — while maintaining full agonist activity at the GHRH receptor (GHRHR) expressed on anterior pituitary somatotrophs.\u003c\/p\u003e\n\n\u003cp\u003eUnlike CJC-1295 With DAC, this version does not incorporate a Drug Affinity Complex and therefore does not form a covalent bond with circulating albumin. The result is a shorter, more physiologically relevant half-life of approximately 30 minutes, producing a discrete, pulsatile pattern of Growth Hormone (GH) secretion that closely mirrors the natural endogenous GH release rhythm. This makes CJC-1295 Without DAC of particular interest in research contexts where pulsatility and feedback regulation of the GH axis are relevant study parameters.\u003c\/p\u003e\n\n\u003cp\u003eThis 10mg\/3ml vial is the mid-range format in our CJC-1295 Without DAC range, offering a practical quantity for extended research protocols. Supplied as a sterile lyophilised powder for reconstitution with Bacteriostatic Water or Acetic Acid Water.\u003c\/p\u003e\n\n\u003ch3\u003eKey Features\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eModified GHRH(1-29) analog — four amino acid substitutions for enhanced enzymatic stability\u003c\/li\u003e\n\u003cli\u003eWithout DAC — no albumin binding; pulsatile GH release pattern preserved\u003c\/li\u003e\n\u003cli\u003e~30-minute half-life — discrete GH secretion pulse, not sustained elevation\u003c\/li\u003e\n\u003cli\u003eFull GHRHR agonist activity — preserves somatostatin feedback regulation\u003c\/li\u003e\n\u003cli\u003e≥99% purity — independently HPLC-verified on every production batch\u003c\/li\u003e\n\u003cli\u003eCertificate of Analysis (COA) provided with every order\u003c\/li\u003e\n\u003cli\u003e10mg\/3ml — mid-range research vial; 2× the content of the 5mg format\u003c\/li\u003e\n\u003cli\u003eLyophilised powder — stable, long shelf life when stored correctly\u003c\/li\u003e\n\u003cli\u003eFast UK dispatch — same-day available on weekday orders placed before 2pm\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eCJC-1295 Without DAC vs With DAC — Key Differences\u003c\/h3\u003e\n\u003ctable\u003e\n\u003ctr\u003e\n\u003cth\u003eProperty\u003c\/th\u003e\n\u003cth\u003eWithout DAC (this product)\u003c\/th\u003e\n\u003cth\u003eWith DAC\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAlbumin binding\u003c\/td\u003e\n\u003ctd\u003eNo\u003c\/td\u003e\n\u003ctd\u003eYes — covalent via maleimide\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHalf-life\u003c\/td\u003e\n\u003ctd\u003e~30 minutes\u003c\/td\u003e\n\u003ctd\u003e6–8 days\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eGH release pattern\u003c\/td\u003e\n\u003ctd\u003ePulsatile (physiological)\u003c\/td\u003e\n\u003ctd\u003eSustained \/ blunted\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSomatostatin feedback\u003c\/td\u003e\n\u003ctd\u003ePreserved\u003c\/td\u003e\n\u003ctd\u003ePartially overridden\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAlso known as\u003c\/td\u003e\n\u003ctd\u003eMod GRF 1-29\u003c\/td\u003e\n\u003ctd\u003eCJC-1295 DAC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\n\u003ch3\u003eSpecifications\u003c\/h3\u003e\n\u003ctable\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePeptide name\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eCJC-1295 Without DAC (Modified GRF 1-29)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eAlso known as\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eMod GRF 1-29, GHRH(1-29) analog, Sermorelin analog\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular formula\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eC₁₅₂H₂₅₂N₄₄O₄₂\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e3,367.97 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eVial content\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e10mg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eVial volume\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e3ml\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePurity\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e≥99% (HPLC verified)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eForm\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eLyophilised powder\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eReconstitution\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eBacteriostatic Water or Acetic Acid Water (0.6%)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStorage (lyophilised)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e−20°C; protect from light and moisture\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eStorage (reconstituted)\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e2–8°C; use within 14–21 days\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCAS number\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e863288-34-0\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eGrade\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eResearch Use Only\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eOrigin\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eUK-based supply and dispatch\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\n\u003ch3\u003eReconstitution Guidance\u003c\/h3\u003e\n\u003cp\u003eReconstitute with Bacteriostatic Water for Injection. Add the diluent slowly down the inner wall of the vial — do not inject directly onto the lyophilised cake. Swirl gently to dissolve; do not vortex or shake. Allow to stand 2–3 minutes until fully clear and colourless. Store refrigerated at 2–8°C and use within 14–21 days of reconstitution.\u003c\/p\u003e\n\n\u003ch3\u003eFrequently Paired With\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIpamorelin\u003c\/strong\u003e — selective GHS-R agonist; commonly studied alongside CJC-1295 Without DAC for dual GHRH + ghrelin receptor pathway research\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCJC-1295 + Ipamorelin Blend (5mg\/5mg)\u003c\/strong\u003e — pre-combined convenience vial available in our range\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBacteriostatic Water 10ml\u003c\/strong\u003e — recommended reconstitution diluent\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eAlso Available In\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCJC-1295 Without DAC 5mg \/ 3ml\u003c\/strong\u003e — entry-level research vial\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003e\u003cem\u003eFor research use only. Not intended for human consumption, self-administration, or veterinary use. This product is sold strictly for in vitro and laboratory research purposes. Ultra Peptides accepts no liability for misuse.\u003c\/em\u003e\u003c\/p\u003e","brand":"Ultra Peptides","offers":[{"title":"Default Title","offer_id":47496741912770,"sku":null,"price":49.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0742\/4481\/7090\/files\/CJC1295-_WIHTOUT-DAC_---10mg---3ml.png?v=1776892237","url":"https:\/\/ultrapeptides.co.uk\/products\/cjc-1295-10mg-3ml-research-peptide-without-dac","provider":"Ultra Peptides","version":"1.0","type":"link"}